Payload is the carrying capacity of a vehicle, often an aircraft or spacecraft.
Payload may also refer to:
- Payload (computing), several analogous usages
- a game mode in Team Fortress 2 and other first-person shooters, in which the attacking team must push a bomb to the defending base
- Payload (EP), an EP by Hunters & Collectors
- Payload (G.I. Joe), several versions of a character or its toy from the G.I. Joe franchise