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Names | |
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Preferred IUPAC name
N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
DrugBank | |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C13H18N2O5S | |
Molar mass | 314.36 g·mol−1 |
Appearance | Off-white solid |
Insoluble | |
Solubility in DMSO | 5 mg/mL |
Hazards | |
GHS labelling:[1] | |
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Warning | |
H302, H312, H332 | |
P280 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.[2]
See also
- Celecoxib
- Tilmacoxib (JTE-522)
References
- ^ "N194 NS-398". Sigma-Aldrich. Retrieved 13 December 2021.
- ^ Wei Shen; Yong Li; Ying Tang; James Cummins; Johnny Huard (2005). "NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis". American Journal of Pathology. 167 (4): 1105–1117. doi:10.1016/S0002-9440(10)61199-6. PMC 1603662. PMID 16192645.