Monoclonal antibody | |
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Type | Whole antibody |
Source | Human |
Target | Pseudomonas aeruginosa serotype IATS O11 |
Clinical data | |
ATC code |
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Identifiers | |
CAS Number | |
ChemSpider |
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UNII | |
Chemical and physical data | |
Formula | C38714H60189N10637O12187S322 |
Molar mass | 879959.96 g·mol−1 |
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Panobacumab (proposed INN) is a monoclonal antibody designed as an antibacterial against Pseudomonas aeruginosa.[1]
It is a fully human pentameric IgM antibody with a mouse J chain.[1]
![](https://upload.wikimedia.org/wikipedia/commons/thumb/f/f3/IgM.png/220px-IgM.png)
1: Base unit.
2: Heavy chains.
3: Light chains.
4: J chain.
5: Intermolecular disulfide bonds.
Development
Panobacumab is being developed by Aridis Pharmaceuticals. As of November 15th it is in phase 2 clinical trials. The originator was Berna Biotech.[2]
The mechanism of action is as a lipopolysaccharide inhibitor.[2]
References
- ^ a b International Nonproprietary Names for Pharmaceutical Substances (INN, prepublication copy), World Health Organization.
- ^ a b "Panobacumab - Aridis Pharmaceuticals - AdisInsight". Retrieved 15 November 2019.