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Names | |
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IUPAC name
(3S,4R)-3-(Carboxymethyl)-4-isopropyl-L-proline
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Systematic IUPAC name
(2S,3S,4R)-3-(2-Hydroxy-2-oxoethyl)-4-(propan-2-yl)pyrrolidine-2-carboxylic acid | |
Other names
Dihydrokainate; DHK
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Identifiers | |
3D model (JSmol)
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84942 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C10H17NO4 | |
Molar mass | 215.249 g·mol−1 |
Hazards | |
GHS labelling: | |
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Warning | |
H302, H312, H332 | |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dihydrokainic acid is an organic compound that contains two carboxylic acid functional groups, making it a dicarboxylic acid. It is an inhibitor of the GLT-1 glutamate transporter.[1]
See also
References
- ^ Kawahara, K; Hosoya, R; Sato, H; Tanaka, M; Nakajima, T; Iwabuchi, S (2002). "Selective blockade of astrocytic glutamate transporter GLT-1 with dihydrokainate prevents neuronal death during ouabain treatment of astrocyte/neuron cocultures". Glia. 40 (3): 337–49. doi:10.1002/glia.10133. hdl:2115/5937. PMID 12420313. S2CID 14246291.