Clinical data | |
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Pregnancy category | |
Routes of administration | Oral |
ATC code | |
Pharmacokinetic data | |
Bioavailability | >95% |
Metabolism | Hepatic |
Elimination half-life | 12.5 ± 1.6 hours |
Excretion | Renal |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.004.325 |
Chemical and physical data | |
Formula | C13H16N2O2 |
Molar mass | 232.278 g/mol |
Aminoglutethimide is an aromatase inhibitor used in the treatment of breast cancer and Cushing's syndrome. It blocks the synthesis of estrogen. Its major side effects are liver toxicity and inhibition of Cortisol in the human body. Since cortisol helps break down muscle, Aminoglutethimide is used by bodybuilders in a steroid cycle.
Reference Links
Aminoglutethimide (Cytadren) Profile