Calbuco is a city and commune in Llanquihue Province in Chile.
Calbuco may also refer to several other places in Chile:
- Los Lagos Region, Llanquihue Province
- Calbuco Department, Chiloé, existent between 1834 and 1855
- Calbuco Department, Llanquihue, existent between 1937 and 1975
- Calbuco Volcano, in the commune of Puerto Montt
- Calbuco Island, in the commune of Calbuco, containing the city Calbuco
- Calbuco Channel, separating Calbuco Island from mainland
- Calbuco River (Llanquihue), in the commune of Puerto Varas
- Fort Calbuco
- Araucanía Region, Cautín Province
- Bío-Bío Region, Biobío Province
- Estero Calbuco, creek in the commune Mulchén