Calbuco is a city and commune in Llanquihue Province in Chile.
Calbuco may also refer to several other places in Chile:
- In the area of todays Llanquihue Province, Los Lagos Region
- Calbuco (volcano), in the commune of Puerto Montt
- Calbuco Department, Chiloé, existing between 1834 and 1855
- Calbuco Department, Llanquihue, existing between 1937 and 1975
- Calbuco Island, in the commune of Calbuco, containing the city Calbuco
- Fort Calbuco, founded in the area of nowadays commune of Calbuco
- Calbuco Channel, separating Calbuco Island from mainland
- Calbuco River (Llanquihue), in the commune of Puerto Varas
- Outside Llanquihue Province
- Calbuco River (Cautín), Cautín Province, Araucanía Region
- Estero Calbuco, creek in the commune Mulchén, Biobío Province, Bío-Bío Region