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{{Drugbox |
{{Drugbox |
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| verifiedrevid = 464380960 |
| verifiedrevid = 464380960 |
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| IUPAC_name = methyl (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-{[(2''E'')-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}yohimban-16-carboxylate |
| IUPAC_name = methyl (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-<nowiki/>{[(2''E'')-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}yohimban-16-carboxylate |
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| image = Rescinnamine.svg |
| image = Rescinnamine.svg |
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| width = 300 |
| width = 300 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = SZLZWPPUNLXJEA-QEGASFHISA-N |
| StdInChIKey = SZLZWPPUNLXJEA-QEGASFHISA-N |
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| synonyms = <small>methyl (1''R'',15''S'',17''R'',18''R'',19''S'',20''S'')-6,18-dimethoxy-17-{[(2''E'')-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.0<sup>2,10</sup>.0<sup>4,9</sup>.0<sup>15,20</sup>]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate</small> |
| synonyms = <small>methyl (1''R'',15''S'',17''R'',18''R'',19''S'',20''S'')-6,18-dimethoxy-17-<nowiki/>{[(2''E'')-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.0<sup>2,10</sup>.0<sup>4,9</sup>.0<sup>15,20</sup>]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate</small> |
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'''Rescinnamine''' is an [[ACE inhibitor|angiotensin-converting enzyme inhibitor]] used as an [[antihypertensive]] [[medication|drug]]. |
'''Rescinnamine''' is an [[ACE inhibitor|angiotensin-converting enzyme inhibitor]] used as an [[antihypertensive]] [[medication|drug]]. |
Revision as of 12:29, 11 April 2017
Clinical data | |
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Trade names | Moderil, Cinnasil, Anaprel |
Other names | methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate |
Routes of administration | oral |
ATC code | |
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Identifiers | |
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ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.042.232 |
Chemical and physical data | |
Formula | C35H42N2O9 |
Molar mass | 634.716 g/mol g·mol−1 |
3D model (JSmol) | |
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Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.
It is an vinca alkaloid obtained from Rauwolfia serpentina[1] and other species of Rauwolfia.[2]
Brand names
Moderil, Cinnasil, Anaprel
References
- ^ FIFE R, MACLAURIN JC, WRIGHT JH (December 1960). "Rescinnamine in treatment of hypertension in hospital clinic and in general practice". British Medical Journal. 2 (5216): 1848–50. doi:10.1136/bmj.2.5216.1848. PMC 2098607. PMID 13699407.
- ^ Balsevich J, Constabel F, Kurz WG (1982). "Alkaloids of Vinca major cv. Variegata". Planta Med. 44 (2): 91–3. doi:10.1055/s-2007-971409. PMID 17402086.