Deep Space may refer to:
NASA
- Deep Space Network (disambiguation), international network of satellite ground stations
- Goldstone Deep Space Communications Complex, satellite ground station in California, US
- Madrid Deep Space Communication Complex, satellite ground station in Spain
- Canberra Deep Space Communication Complex, satellite ground station in Australia
- Deep Space 1, spacecraft
- Deep Space 2, two highly advanced miniature probes
Astronomy
- Empty regions of the universe in outer space
- Interstellar space
- Intergalactic space
Other fields
- Deep Space (film), a 1988 horror sci-fi movie
- Deep Space (music), Saturday late night/early morning radio show on WGPR 107.5 FM in Detroit
- Deep Space (collection), a 1954 collection of short stories by Eric Frank Russell
- Deep Space (EP), an EP by Eisley
- Deep Space, a video game company and subsidiary of Sony Computer Entertainment
- Deep Space Industries, an American company developing and producing spacecraft technology
- "Deep Space", a song by Blank Banshee from the album Blank Banshee 0
- "Deep Space", a song by Sub Focus from the album Sub Focus