Mike or Michael James may refer to:
- Mickie James (born 1979), American professional wrestler
- Mike James (American football) (born 1991), American football running back
- Michael James, American musician with Explosions in the Sky
- Michael James (Australian footballer) (born 1971), Australian rules footballer
- Mike James (baseball) (born 1967), American baseball player
- Mike James (basketball, born 1975), American basketball player
- Mike James (basketball, born 1990), American basketball player
- Michael James (cricketer, born 1934), English cricketer
- Michael James (cricketer, born 1987), English cricketer
- Michael James (politician) (1861–1943), Canadian politician of the early 20th century
- Michael James (producer) (born 1962), American record producer, guitarist, and mixing engineer
- Michael James (quilt artist) (born 1949), American artist
- Michael James (writer), pseudonym of a British writer, educator and illustrator
- Mike James (rugby union) (born 1973), Canadian rugby union player
- Michael James (singer), British singer and songwriter
- Michael N. G. James (born 1940), professor of biochemistry at the University of Alberta
See also
- All pages with titles beginning with Michael James
- James Michael (disambiguation)