Take Care may refer to:
- Take Care (album), a 2011 album by Drake
- "Take Care" (song), its title song
- Take Care (film), a 2014 comedy-drama film
- "Take Care", a 1956 song by Jane Morgan
- "Take Care," a 1978 song by Big Star from Third
- "Take Care", a 2006 song by Janet Jackson from 20 Y.O.
- "Take Care", a 2010 song by Beach House from Teen Dream
- "Take Care", a 2011 song by Jennifer Lopez from Love?
- "take care", a 2018 song by Eden from vertigo
- Take Care, a program developed by primatologist Jane Goodall for creating microcredit banks and educating conservation methods to inhabitants near forests and national parks, such as Gombe National Park
See also
- Take Care, Take Care, Take Care, a 2011 album by Explosions in the Sky