Texas v · d · Neoplasm: Tumor suppressor genes/proteins and Oncogenes/Proto-oncogenes Ligand Growth factors ONCO: c-Sis/PDGF · HGF Receptor Wnt signaling pathway TSP: CDH1 Hedgehog signaling pathway TSP: PTCH1 TGF beta signaling pathway TSP: TGF beta receptor 2 Receptor tyrosine kinase ONCO: ErbB/c-ErbB (HER2/neu, Her 3) - c-Met - c-Ret JAK-STAT signaling pathway ONCO: c-Kit - Flt3 Intracellular signaling P+Ps Wnt signaling pathway ONCO: Beta-catenin · TSP: APC TGF beta signaling pathway TSP: SMAD2, SMAD4 Akt/PKB signaling pathway TSP: PTEN · ONCO: c-Akt Hippo signaling pathway TSP: Neurofibromin 2/Merlin MAPK/ERK pathway TSP: Neurofibromin 1 · ONCO: c-Ras/HRAS, c-Raf Other/unknown TSP: Maspin · ONCO: c-Src Nucleus Cell cycle TSP: p53 · pRb · WT1 · p16/p14arf · ONCO: CDK4 · Cyclin D · Cyclin E DNA repair/Fanconi ONCO: BRCA1 - BRCA2 Ubiquitin ligase TSP: VHL · ONCO: CBL - MDM2 Transcription factor TSP: KLF6 · ONCO: AP-1 (c-Fos, c-Jun) - c-Myc Mitochondria Apoptosis inhibitor: SDHB - SDHD Other/ungrouped c-Bcl-2 - Notch - Stathmin M: NEO tsoc, mrkr tumr, epon, para drug (L1i/1e/V03) Personal tools Log in / create account Namespaces Template Discussion Variants Views Read View history Actions Search Navigation Main page Contents Featured content Current events Random article Donate to Wikipedia Interaction Help About Wikipedia Community portal Recent changes Contact Wikipedia Toolbox What links here Related changes Upload file Special pages Permanent link