General transcription factor IIIA | |||||||||||||
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Identifiers | |||||||||||||
Symbols | GTF3A ; AP2; TFIIIA | ||||||||||||
External IDs | OMIM: 600860 HomoloGene: 55630 GeneCards: GTF3A Gene | ||||||||||||
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Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 2971 | 66596 | |||||||||||
Ensembl | ENSG00000122034 | ENSMUSG00000016503 | |||||||||||
UniProt | Q92664 | Q8VHT7 | |||||||||||
RefSeq (mRNA) | NM_002097 | NM_025652 | |||||||||||
RefSeq (protein) | NP_002088 | NP_079928 | |||||||||||
Location (UCSC) | Chr 13: 28 – 28.01 Mb |
Chr 5: 146.95 – 146.96 Mb |
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PubMed search | [1] | [2] | |||||||||||
Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.[1][2]
References
- ^ Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenet Cell Genet 70 (3–4): 235–8. doi:10.1159/000134041. PMID 7789179.
- ^ "Entrez Gene: GTF3A general transcription factor IIIA".
Further reading
- Murphy JE, Keen JH (1992). "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia". J. Biol. Chem. 267 (15): 10850–5. PMID 1587861.
- Seifart KH, Wang L, Waldschmidt R et al. (1989). "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA". J. Biol. Chem. 264 (3): 1702–9. PMID 2912980.
- Drew PD, Nagle JW, Canning RD et al. (1995). "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA". Gene 159 (2): 215–8. doi:10.1016/0378-1119(95)00145-V. PMID 7622052.
- Moorefield B, Roeder RG (1994). "Purification and characterization of human transcription factor IIIA". J. Biol. Chem. 269 (33): 20857–65. PMID 8063702.
- Fridell RA, Fischer U, Lührmann R et al. (1996). "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev". Proc. Natl. Acad. Sci. U.S.A. 93 (7): 2936–40. doi:10.1073/pnas.93.7.2936. PMC 39738. PMID 8610146.
- Oettel S, Härtel F, Kober I et al. (1997). "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes". Nucleic Acids Res. 25 (12): 2440–7. doi:10.1093/nar/25.12.2440. PMC 146769. PMID 9171097.
- Moreland RJ, Dresser ME, Rodgers JS et al. (2000). "Identification of a transcription factor IIIA-interacting protein". Nucleic Acids Res. 28 (9): 1986–93. doi:10.1093/nar/28.9.1986. PMC 103300. PMID 10756201.
- Rao DS, Chang JC, Kumar PD et al. (2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors". Mol. Cell. Biol. 21 (22): 7796–806. doi:10.1128/MCB.21.22.7796-7806.2001. PMC 99949. PMID 11604514.
- Hanas JS, Hocker JR, Cheng YG et al. (2002). "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA". Gene 282 (1–2): 43–52. doi:10.1016/S0378-1119(01)00796-X. PMID 11814676.
- Weser S, Riemann J, Seifart KH, Meissner W (2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene". Nucleic Acids Res. 31 (9): 2408–16. doi:10.1093/nar/gkg345. PMC 154231. PMID 12711686.
- Pellikainen JM, Ropponen KM, Kataja VV et al. (2005). "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis". Clin. Cancer Res. 10 (22): 7621–8. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.
- Paing MM, Johnston CA, Siderovski DP, Trejo J (2006). "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization". Mol. Cell. Biol. 26 (8): 3231–42. doi:10.1128/MCB.26.8.3231-3242.2006. PMC 1446942. PMID 16581796.
- Yamashita A, Takada T, Nemoto K et al. (2006). "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage". FEBS Lett. 580 (17): 4121–5. doi:10.1016/j.febslet.2006.06.057. PMID 16828750.
- Schwartz B, Melnikova VO, Tellez C et al. (2007). "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo". Oncogene 26 (28): 4049–58. doi:10.1038/sj.onc.1210193. PMID 17224907.
- Hannay JA, Liu J, Zhu QS et al. (2007). "Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation". Mol. Cancer Ther. 6 (5): 1650–60. doi:10.1158/1535-7163.MCT-06-0636. PMID 17513613.
External links
- GTF3A protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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