INSL6 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | INSL6, RIF1, insulin like 6 | ||||||||||||||||||||||||
External IDs | OMIM: 606414 MGI: 1351595 HomoloGene: 5197 GeneCards: INSL6 | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
UniProt | |||||||||||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) | |||||||||||||||||||||||||
Location (UCSC) | Chr 9: 5.12 – 5.19 Mb | Chr 19: 29.3 – 29.3 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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Insulin like 6 is a protein that in humans is encoded by the INSL6 gene. [5]
Function
The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. This gene is preferentially expressed in testis. Its expression in testis is restricted to interstitial cells surrounding seminiferous tubules, which suggests a role in sperm development and fertilization.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000120210 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050957 - Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Insulin like 6". Retrieved 2016-02-25.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.